Creator:

Banerjee, Sandip

Contributor:

Gałkowski, Krzysztof - ed. ; Rogers, Eric - ed. ; Willems, Jan

Title:

Immunotherapy with interleukin-2: A study based on mathematical modeling

Subtitle:

.

Group publication title:

AMCS, volume 18 (2008)

Subject and Keywords:

effector cells ; tumor cells ; interleukin-2 ; discrete time delay

Abstract:

The role of interleukin-2 (IL-2) in tumor dynamics is illustrated through mathematical modeling, using delay differential equations with a discrete time delay (a modified version of the Kirshner-Panetta model). Theoretical analysis gives an expression for the discrete time delay and the length of the time delay to preserve stability. Numerical analysis shows that interleukin-2 alone can cause the tumor cell population to regress.

Publisher:

Zielona Góra: Uniwersytet Zielonogórski

Date:

2008

Resource Type:

artykuł

DOI:

10.2478/v10006-008-0035-6

Pages:

389-398

Source:

AMCS, volume 18, number 3 (2008) ; click here to follow the link

Language:

eng

License CC BY 4.0:

click here to follow the link

Rights:

Biblioteka Uniwersytetu Zielonogórskiego