@misc{Ferdania_Devi_Fitri_Minimal, author={Ferdania, Devi Fitri and Irawati and Garminia, Hanni and Akhmaloka and Rachmansyah, Kemal Aziez}, howpublished={online}, publisher={Zielona Góra: Uniwersytet Zielonogórski}, language={eng}, abstract={Beta-thalassemia is an autosomal recessive blood disorder characterized by abnormalities in the synthesis of ß globin. Together with [alpha] globin, it is a subunit of globin protein, called hemoglobin, located inside our red blood cells to deliver oxygen from the lungs to all of the tissues throughout our body. Thereby, individuals with ß-thalassemia will often feel limp due to a lack of oxygen dissolved in their blood.}, abstract={In this paper, a finite state automaton to detect and classify ß globin gene mutations using its DNA sequence is constructed. Finite state automata have a close connection to an algebraic structure, that is, a monoid. Together with the theory of the syntactic monoid, we present a methodology to minimize the number of the internal states of an automaton to have minimal state automata. Therefore, a minimal state automaton can be constructed to detect ß globin gene mutation causing the ß-thalassemia disease. We have developed a MATLAB program to conduct the appropriate simulations.}, type={artykuł}, title={Minimal state automata for detecting a ß globin gene mutation}, keywords={minimal state automata, syntactic monoid, ß-thalassemia, biological sequences}, }