Szukana fraza: [Abstract = "Recently, we have proposed a gradient\-based algorithm for the optimization of a sampling schedule. In this paper we use the algorithm in order to optimize a sampling schedule for the identification of the mathematical model of the NF\?B regulatory module, known from the literature. We propose a two\-stage optimization approach\: a gradient\-based procedure to find all stationary points and then pair\-wise replacement for finding optimal numbers of replicates of measurements. Convergence properties of the presented algorithm are examined."]