Object
Title: A model of cell growth and possibilities of tumour treatment by selective protein depletion
Contributor:
Kimmel, Marek - red. ; Świerniak, Andrzej - red.
Subtitle:
Control and Modeling of Cancer Cell Population
Group publication title:
Abstract:
A simple model of a self-enlarging synthesizing unit with the growth-limiting assumptions on precursor transport losses and product turnover is used as a prototype dynamic system for a cell growth model. The model successfully describes the main features of cell growth and allows for a rational discussion of the cell cycle. The cell is viewed as a non-linear capacitance damped by transport losses. ; If transformation results in a fundamental dynamic difference in growth parameters of the cell, an intriguing possibility exists that a mixed pool of normal and transformed cells connected to a common source of nutrients may constitute a point-wise controllable system. Most of the cell mass is protein, the building blocks are amino acids and the systemic concentration of one of the essential acids is proposed as the control input. ; A rather simple strategy of control capitalizes on the presumed difference in the cycle dynamics and suggests a possibility for a selective protein depletion of transformed cells based on what underscores the very danger of tumours - their propensity to grow and proliferate under conditions in which normal cells would not do so.
Publisher:
Zielona Góra: Uniwersytet Zielonogórski
Resource Identifier:
Pages:
Source:
AMCS, volume 4, number 2 (1994) ; click here to follow the link
Language:
Rights:
Biblioteka Uniwersytetu Zielonogórskiego
Object collections:
- Digital Library of Zielona Góra > Repository > Faculties > Faculty of Computer, Electrical and Control Engineering
- Digital Library of Zielona Góra > Repository > Types of work > Articles
- Digital Library of Zielona Góra > Repository > Scientific journals and UZ publishing series > International Journal of Applied Mathematics and Computer Science (AMCS)
- Digital Library of Zielona Góra > Repository > Scientific journals and UZ publishing series > International Journal of Applied Mathematics and Computer Science (AMCS) > International Journal of Applied Mathematics and Computer Science (AMCS) (1994)
Last modified:
Sep 1, 2021
In our library since:
Jul 27, 2020
Number of object content hits:
83
All available object's versions:
https://zbc.uz.zgora.pl/publication/63918
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International Journal of Applied Mathematics and Computer Science (AMCS)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 26 (2016)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 25 (2015)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 24 (2014)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 23 (2013)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 22 (2012)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 21 (2011)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 20 (2010)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 19 (2009)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 18 (2008)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 17 (2007)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 16 (2006)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 15 (2005)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 13 (2003)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 12 (2002)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 11 (2001)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 10 (2000)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 9 (1999)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 8 (1998)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 7 (1997)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 6 (1996)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 5 (1995)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 4 (1994)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 4, number 1 (1994)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 4, number 2 (1994)
- Rapid genome evolution, cancer and heritable diseases: a modelling perspective
- A model of cell growth and possibilities of tumour treatment by selective protein depletion
- Distributed modelling of cell population
- Controllability of non-linear models in modelling population dynamics
- A nondifferentiable semigroup generated by a model of cell population dynamics
- Some control problems for simplest differential models of proliferation cycle
- Deterministic and stochastic modelling of tumour growth and optimal chemotherapy
- H[znak nieskończoności]-methods in population modelling and control
- Mathematical methods for cell cycle analysis from flow cytometric DNA-BrdUrd distributions
- Evaluation of some optimal chemotherapy protocols by using a gradient method
- Irregularity in scheduling of cancer chemotherapy
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 4, number 3 (1994)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 4, number 4 (1994)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 4, number 1 (1994)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 3 (1993)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 2 (1992)
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International Journal of Applied Mathematics and Computer Science (AMCS),volume 1 (1991)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 26 (2016)
| Edition name | Date |
|---|---|
| A model of cell growth and possibilities of tumour treatment by selective protein depletion | Sep 1, 2021 |
