Cell manipulation using external magnetic fields has been proposed to accelerate the neck reendothelization of saccular unruptured stented intracranial aneurysms. This work presents a computational fluid dynamics (CFD) model of a Saccular Brain Aneurysm that incorporates a helicoidal stent. ; An Eulerian-Lagrangian model implemented in ANSYS-Fluent is used to simulate the hemodynamics in the aneurysm. In silico studies have been conducted to describe the incidence of the magnetic field direction, frequency and amplitude on the blood hemodynamics and particle capture efficiency, when an external magnetic field is used to trap magnetically labeled particles traveling through the aneurysm. ; It is found that the magnetic field direction affects the particle concentration in the target region. Simulation results show that the highest particle capture efficiency is obtained with a 1T magnetic field amplitude in an open bore MRI scanner, when a permanent magnet is used.
Zielona Góra: Uniwersytet Zielonogórski
IJAME, volume 26, number 1 (2021)
Biblioteka Uniwersytetu Zielonogórskiego
Jul 6, 2023
Feb 6, 2023
59
https://zbc.uz.zgora.pl/publication/77574
Edition name | Date |
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Capture efficiency of magnetically labeled particles traveling through an intracranial aneurysm | Jul 6, 2023 |
Rodríguez, L. Lain, Santiago Benavides-Moran, Aldo Jurczak, Paweł - red.
Merah, Aissa Noureddine, Abdelkader Jurczak, Paweł - red.
Piechna, Adam Cieślicki, Krzysztof Jurczak, Paweł - red.
Jain, Shalini Bohra, Shweta Jurczak, Paweł - red.
Linga Raju, Temburu Nagavalli, Madhupada Jurczak, Paweł - red.
Singh, K.D. Jurczak, Paweł - red.
Makhalemele, Cynthia Rundora, Lazarus Adesanya, Samuel Olumide Jurczak, Paweł - red.
Mesbah, Abderaouf Allouaoui, Reda Bouazis, Amina Manal Bouazis, Mohamed Najib Jurczak, Paweł - red.