Obiekt

Tytuł: Minimal state automata for detecting a ß globin gene mutation

Współtwórca:

Korbicz, Józef (1951- ) - red. ; Uciński, Dariusz - red.

Tytuł publikacji grupowej:

AMCS, volume 31 (2021)

Abstract:

Beta-thalassemia is an autosomal recessive blood disorder characterized by abnormalities in the synthesis of ß globin. Together with [alpha] globin, it is a subunit of globin protein, called hemoglobin, located inside our red blood cells to deliver oxygen from the lungs to all of the tissues throughout our body. Thereby, individuals with ß-thalassemia will often feel limp due to a lack of oxygen dissolved in their blood. ; In this paper, a finite state automaton to detect and classify ß globin gene mutations using its DNA sequence is constructed. Finite state automata have a close connection to an algebraic structure, that is, a monoid. Together with the theory of the syntactic monoid, we present a methodology to minimize the number of the internal states of an automaton to have minimal state automata. Therefore, a minimal state automaton can be constructed to detect ß globin gene mutation causing the ß-thalassemia disease. We have developed a MATLAB program to conduct the appropriate simulations.

Wydawca:

Zielona Góra: Uniwersytet Zielonogórski

Identyfikator zasobu:

oai:zbc.uz.zgora.pl:86279

DOI:

10.34768/amcs-2021-0023

Strony:

337-351

Źródło:

AMCS, volume 31, number 2 (2021) ; kliknij tutaj, żeby przejść

Jezyk:

eng

Licencja CC BY 4.0:

kliknij tutaj, żeby przejść

Prawa do dysponowania publikacją:

Biblioteka Uniwersytetu Zielonogórskiego

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