Object
Title: Model based analysis of signaling pathways
Contributor:
Kasiński, Andrzej - ed. ; Ponulak, Filip - ed.
Subtitle:
Group publication title:
Abstract:
The paper is concerned with application of mathematical modeling to the analysis of signaling pathways. Two issues, deterministic modeling of gene transcription and model-driven discovery of regulatory elements, are dealt with. First, the biological background is given and the importance of the stochastic nature of biological processes is addressed. The assumptions underlying deterministic modeling are presented. Special emphasis is put on describing gene transcription. ; A framework for including unknown processes activating gene transcription by means of first-order lag elements is introduced and discussed. Then, a particular interferon-? induced pathway is introduced, limited to early events that precede activation of gene transcription. It is shown how to simplify the system description based on the goals of modeling. Further, a computational analysis is presented, facilitating better understanding of the mechanisms underlying regulation of key components in the pathway. The analysis is illustrated by a comparison of simulation and experimental data.
Publisher:
Zielona Góra: Uniwersytet Zielonogórski
Resource Identifier:
DOI:
Pages:
Source:
AMCS, volume 18, number 2 (2008) ; click here to follow the link
Language:
Rights:
Biblioteka Uniwersytetu Zielonogórskiego
Object collections:
- Repository > Faculties > Faculty of Computer, Electrical and Control Engineering
- Repository > Types of work > Articles
- Repository > Scientific journals and UZ publishing series > International Journal of Applied Mathematics and Computer Science (AMCS) > International Journal of Applied Mathematics and Computer Science (AMCS) (2008)
Last modified:
Apr 8, 2024
In our library since:
Apr 5, 2024
Number of object content hits:
8
All available object's versions:
https://zbc.uz.zgora.pl/repozytorium/publication/88465
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International Journal of Applied Mathematics and Computer Science (AMCS)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 26 (2016)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 25 (2015)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 24 (2014)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 23 (2013)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 22 (2012)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 21 (2011)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 20 (2010)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 19 (2009)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 18 (2008)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 18, number 1 (2008)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 18, number 2 (2008)
- Analysis of the ReSuMe learning process for spiking neural networks
- Towards spike-based speech processing: A biologically plausible approach to simple acoustic classification
- Model based analysis of signaling pathways
- A new approach to image reconstruction from projections using a recurrent neural network
- Segmentation of breast cancer fine needle biopsy cytological images
- How to compensate a spreading disturbance for a class of nonlinear systems
- Time-optimal boundary control of an infinite order parabolic system with time lags
- Approximate controllability of infinite dimensional systems of the n-th order
- Controllability and observability of linear discrete-time fractional-order systems
- Fractional positive continuous-time linear systems and their reachability
- Extension of first order predictive functional controllers to handle higher order internal models
- Inferring graph grammars by detecting overlap in frequent subgraphs
- Creation of unequal error protection codes for two groups of symbols
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 18, number 3 (2008)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 18, number 4 (2008)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 18, number 1 (2008)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 17 (2007)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 16 (2006)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 15 (2005)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 13 (2003)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 12 (2002)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 11 (2001)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 10 (2000)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 9 (1999)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 8 (1998)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 7 (1997)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 6 (1996)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 5 (1995)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 4 (1994)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 3 (1993)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 2 (1992)
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International Journal of Applied Mathematics and Computer Science (AMCS),volume 1 (1991)
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International Journal of Applied Mathematics and Computer Science (AMCS), volume 26 (2016)
| Edition name | Date |
|---|---|
| Model based analysis of signaling pathways | Apr 8, 2024 |
