Wyszukiwanie zaawansowane ?

Obiekt

Pobierz

Tytuł: Identifiability and estimation of pharmacokinetic parameters for the ligands of the macrophagemannose receptor

Autor:

Verdiere, Nathalie ; Denis-Vidal, Lilianne ; Joly-Blanchard, Ghislaine ; Domurado, Dominique

Data wydania:

2005

Typ zasobu:

artykuł

Współtwórca:

Beliczyński, Bartłomiej - red.

Podtytuł:

Intelligent Control and Signal Processing

Tytuł publikacji grupowej:

AMCS, Volume 15 (2005)

Abstract:

The aim of this paper is numerical estimation of pharmacokinetic parameters of the ligands of the macrophage mannosereceptor, without knowing "a priori" the values of these parameters. However, it first requires a model identifiability analysis, which is done by applying an algorithm implemented in a symbolic computation language. It is shown that this step can lead to a direct numerical estimation algorithm. In this way, a first estimate is computed from noisy simulated observations without a priori parameter values. Then the resulting parameter estimate is improved by using the classical least-squares method.

Wydawca:

Zielona Góra: Uniwersytet Zielonogórski

Identyfikator zasobu:

oai:zbc.uz.zgora.pl:46812

Strony:

517-526

Źródło:

AMCS, Volume 15, Number 4 (2005) ; kliknij tutaj, żeby przejść

Jezyk:

eng

Licencja CC BY 4.0:

kliknij tutaj, żeby przejść

Prawa do dysponowania publikacją:

Biblioteka Uniwersytetu Zielonogórskiego

Temat i słowa kluczowe:

nonlinear systems identifiability parameter estimation biological applications

Kolekcje, do których przypisany jest obiekt:

Data ostatniej modyfikacji:

14 lip 2025

Data dodania obiektu:

9 sie 2018

Liczba wyświetleń treści obiektu:

251

Wszystkie dostępne wersje tego obiektu:

https://zbc.uz.zgora.pl/repozytorium/publication/54901

Wyświetl opis w formacie RDF:

RDF

Wyświetl opis w formacie OAI-PMH:

OAI-PMH

Nazwa wydania Data
Identifiability and estimation of pharmacokinetic parameters for the ligands of the macrophagemannose receptor 14 lip 2025

Obiekty Podobne

AMCS, Volume 26 (2016)
AMCS, Volume 26 (2016)
Set-membership identifiability of nonlinear models and related parameter estimation properties

Jauberthie, Carine Travé-Massuyes, Louise Verdiere, Nathalie Korbicz, Józef (1951- ) - red. Uciński, Dariusz - red.

2016
artykuł
AMCS, volume 9 (1999)
AMCS, volume 9 (1999)
Parameter estimation based fault detection and isolation in Wiener and Hammerstein systems

Janczak, Andrzej Korbicz, Józef (1951- ) - red. Patton, Ronald J. - red.

1999
artykuł
AMCS, volume 29 (2019)
AMCS, volume 29 (2019)
Two-stage instrumental variables identification of polynomial Wiener systems with invertible nonlinearities

Janczak, Andrzej Korbicz, Józef (1951- ) Kulczycki, Piotr - ed. Kacprzyk, Janusz - ed. Kóczy, László T. - ed. Mesiar, Radko - ed.

2019
artykuł
AMCS, volume 32 (2022)
AMCS, volume 32 (2022)
Parameter identifiability for nonlinear LPV models

Srinivasarengan, Krishnan Ragot, José Aubrun, Christophe Maquin, Didier Witczak, Marcin - ed. Stetter, Ralf - ed.

2022
artykuł
AMCS, volume 28 (2018)
AMCS, volume 28 (2018)
An adaptive observer design approach for a class of discrete-time nonlinear systems

Srinivasarengan, Krishnan Ragot, José Aubrun, Christophe Maquin, Didier Aitouche, Abdel - ed.

2018
artykuł
AMCS, Volume 23 (2013)
AMCS, Volume 23 (2013)
Nonlinear state observers and extended Kalman filters for battery systems

Rauh, Andreas Butt, Saif S. Aschemann, Harald Korbicz, Józef (1951- ) - red. Uciński, Dariusz - red.

2013
artykuł
AMCS, volume 11 (2001)
AMCS, volume 11 (2001)
Identification of a quasilinear parabolic equation from final data

Fernández, Luis A. Pola, Cecilia Triggiani, Roberto- ed. Maksimov, Vyacheslav I. - ed.

2001
artykuł
AMCS, Volume 21 (2011)
AMCS, Volume 21 (2011)
Modeling of reliability characteristics typically assumes that components and systems fail if a certain individual damagelevel is exceeded. Every (mechanical) system damage increases irreversibly due to employed loading and (mechanical)stress, respectively. The main issue of damage estimation is adequate determination of the actual state-of-damage. Severalmathematical modeling approaches are known in the literature, focusing on the task of how loading effects damageprogression (e.g., W¨ohler, 1870) for wear processes. Those models are only valid for specific loading conditions, a prioriassumptions, set points, etc. This contribution proposes a general model, covering adequately the deterioration of a setof comparable systems under comparable loading. The main goal of this contribution is to derive the loading?damageconnection directly from observation without assuming any damage models at the outset. Moreover, the connection is notinvestigated in detail (e.g., to examine the changes in material, etc.) but only approximated with a probabilistic approach.The idea is subdivided into two phases: A problem-specific relation between loading applied (to a structure, which contributesto the stress) and failure is derived from simulation, where a probabilistic approach only assumes a distributionfunction. Subsequently, an adequate general model is set up to describe deterioration progression. The scheme will beshown through simulation-based results and can be used for estimation of the remaining useful life and predictive maintenance/control.Keywords: reliability, parameter estimation, damage accumulation, probabilistic simulation.

Dettmann, Kai-Uwe Söffker, Dirk Korbicz, Józef (1951- ) - red. Uciński, Dariusz - red.

2011
artykuł
Więcej
×

Cytowanie

Styl cytowania:

Dane kontaktowe

Adres

Biblioteka Uniwersytetu Zielonogórskiego
al. Wojska Polskiego 71
65-762 Zielona Góra

Telefon

(+48) 68 328 21 55

E-Mail

repozytorium@uz.zgora.pl

Odwiedź nas!

Ta strona wykorzystuje pliki 'cookies'. Więcej informacji